Human chorionic gonadotropin (HCG) is a naturally occurring placental glycoprotein hormone that interacts with the luteinizing hormone/choriogonadotropin receptor (LHCGR). It is structured as a disulfide-rich heterodimer composed of a common 92-amino-acid alpha subunit and a unique 145-amino-acid beta subunit. In preclinical research, HCG is used to explore luteinizing hormone receptor signaling, reproductive endocrinology, paracrine crosstalk, and angiogenic pathways.
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